Rotamase enzyme activity inhibitors
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United States of America Patent
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Sep 1, 1998
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app pub date -
May 13, 1996
filing date -
Oct 31, 1995
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Abstract
This invention relates to the method of using specially formulated neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
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