Lactose spherical particles and process for their production
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United States of America Patent
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Aug 11, 1998
Grant Date -
N/A
app pub date -
Jan 24, 1997
filing date -
Jan 24, 1996
priority date (Note) -
Expired
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Abstract
To provide spherical particles made substantially from lactose and having high surface smoothness with low abrasiveness, and a process for their production. A process for producing spherical particles containing at least 95 wt % lactose, characterized by comprising a step of producing lactose spherical particles by charging crystalline lactose and/or lactose granules onto a rotary disk in the treatment vessel of a centrifugal tumbling apparatus, dispersing powdered lactose to the lactose granules and/or crystalline lactose as the rotary disk is rotated while providing slit air into the vessel, while also spraying water, an aqueous lactose solution or a dilute aqueous solution of a water-soluble polymer, and a fixation treatment step of drying the obtained spherical particles in a fluidized bed apparatus while spraying an aqueous lactose solution and/or a dilute solution of a water-soluble polymer.
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