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Abstract

The disclosure describes a pharmaceutical composition comprising an aromatase-inhibiting effective amount of a compound selected from the group consisting of compounds of the formula (I): ##STR1## including their stereoisomers and salts thereof, wherein R.sup.1 is halogen or phenyl; m is 0, 1, 2 or 3; k and n each are independently 0, 1 or 2; R.sup.2 and R.sup.3 each are independently H or OH; R.sup.6 and R.sup.7 each are independently H or C.sub.1-4 alkyl; R.sup.8 and R.sup.9 each are H or R.sup.8 and R.sup.9 form --C(R.sup.4) (R.sup.5)--C(R.sup.11) (R.sup.12)-- bond wherein R.sup.4, R.sup.5, R.sup.11 and R.sup.12 each are independently H or C.sub.1-4 alkyl; Y is N or CH; and R.sup.10 is H or halogen, or R.sup.10 combines with R.sup.2 to form --O-- bond, with proviso that if R.sup.8 and R.sup.9 form --C(R.sup.4) (R.sup.5)--C(R.sup.11) (R.sup.2)-- bond, R.sup.3, R.sup.6 and R.sup.7 each are H, and k and n each are 1, then R.sup.2 and R.sup.10 form --O-- bond, and a pharmaceutically acceptable carrier or diluent.

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First Claim