.alpha.-pyrimidinyl acrylic acid derivatives
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United States of America Patent
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Jul 21, 1998
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N/A
app pub date -
May 23, 1996
filing date -
Jan 10, 1995
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Expired
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Abstract
This invention relates to compounds of formula I ##STR1## wherein R.sup.1 is C.sub.1-4 alkoxy or --NR.sup.8 R.sup.9 ; R.sup.2 is heteroaryl, heteroaryloxy or a group ##STR2## R.sup.3 is hydrogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, cyano, nitro or halogen; R.sup.4 is hydrogen, halogen, C.sub.1-4 alkoxy or C.sub.1-4 alkyl; R.sup.5 is hydrogen or methyl; R.sup.7 is hydrogen or methyl; R.sup.8 and R.sup.9 are independently C.sub.1-4 alkyl or together C.sub.3-6 alkylene; E is C.sub.1-3 alkylene; X is CH or nitrogen; and Y is OCH.sub.3, NH.sub.2, NHCH.sub.3 or N(CH.sub.3).sub.2.
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