C-reactive protein fragment with immunomodulatory activity

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United States of America Patent

PATENT NO 5783179
SERIAL NO

07743613

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds having immunomodulatory activity comprising the optionally modified dodecapeptide fragment A-(SEQ ID No: 1)-B corresponding to residues 174 to 185 of C-reactive protein (CRP), pharmaceutical compositions thereof, and methods of treating cancer with the compositions. Liposomal formulations containing the CRP-peptide fragment are particularly efficacious when administered in conjunction with interleukin-2.

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Patent Owner(s)

Patent OwnerAddress
SYNTEX (U S A ) INC3401 HILLVIEW AVENUE PATENT LAW AND LICENSING DEPARTMENT MAILSTOP A2-200 PALO ALTO CA 94304

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barna, Barbara P Berea, OH 1 31
Deodhar, Sharad D Shaker Heights, OH 1 31
Eppstein, Deborah A Palo Alto, CA 18 4176
Felgner, Philip L San Diego, CA 49 6143
Ho, Teresa H Los Altos, CA 7 276
Nestor, Jr John J Cupertino, CA 17 589

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