Sustained and controlled release of water insoluble polypeptides
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United States of America Patent
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Jul 7, 1998
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N/A
app pub date -
Feb 10, 1994
filing date -
Sep 21, 1987
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Abstract
A pharmaceutical composition for the sustained release of a peptide wherein the composition includes a polylactide polymer, a polymer of lactic acid and glycolic acid, or a mixture of such polymers and a therapeutically active peptide in the form of its pamoate, tannate or stearate salt. The composition when placed in an aqueous physiological environment releases the peptide in a continuous manner for a period of at least about one week.
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