Method for identifying T cells involved in autoimmune disease

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United States of America Patent

PATENT NO 5776708
SERIAL NO

08170114

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a method for identifying T cell populations involved in autoimmune diseases. This involves determining levels of a V.beta. element in a body fluid sample of a patient and comparing this to normal levels. Variation from normal levels is indicative of an autoimmune disease. The invention also involves assaying T cell subpopulations in a sample to determine clonality of .beta. chains. Clonality can also be used to diagnose autoimmune disorders.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL JEWISH CENTER FOR IMMUNOLOGY AND RESPIRATORY MEDICINEDENVER CO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kappler, John Denver, CO 9 238
Kotzin, Brian L Denver, CO 4 222
Marrack, Philippa Denver, CO 13 375
Paliard, Xavier Denver, CO 11 180

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