Matrix metalloprotease inhibitors
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United States of America Patent
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Jun 30, 1998
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app pub date -
Feb 5, 1996
filing date -
Aug 5, 1993
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Abstract
Compounds of formula (I): ##STR1## as single stereoisomers or mixtures thereof and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as interstitial collagenases, and are useful in the treatment of mammals having disease states alleviated by the inhibition of such matrix metalloproteases, for example arthritic diseases or bone resorption diseases, such as osteoporosis.
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