Improvements relating to prodrugs
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United States of America Patent
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Jun 23, 1998
Grant Date -
N/A
app pub date -
Apr 19, 1996
filing date -
Jul 27, 1993
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A prodrug of the general formula FTLi-(PRT)m, where m is an integer from 1 to 5; FTLi is a ras inhibitor such as a farnesyltransferase inhibitor compound, such as Ia, Ib, Ic; and PRT represents m protecting groups or a precursor thereof, such as compound XVI, which are capable of being cleaved from the ras inhibitor by the action of a enzyme. ##STR1##
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