Nucleic acid encoding novel human G-protein coupled receptor

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United States of America Patent

PATENT NO 5763218
SERIAL NO

08696770

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Abstract

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Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.

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Patent Owner(s)

Patent OwnerAddress
HUMAN GENOME SCIENCES9410 KEY WEST AVENUE ROCKVILLE MD 20850
TEKEDA1-1 DOSHGOMACHI 4-CHROME CHUO-KU OSAKA 541

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujii, Ryo Tsukuba, JP 68 645
Hinuma, Shuji Tsukuba, JP 72 402
Li, Yi Gaithersburg, MD 917 5421
Ruben, Steven M Olney, MD 693 8435
Soppet, Daniel R Centreville, VA 161 830

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