Process for detecting potential carcinogens
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United States of America Patent
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Jun 9, 1998
Issued Date -
N/A
app pub date -
Jun 27, 1994
filing date -
Dec 23, 1987
priority date (Note) -
Expired
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Abstract
A process is described for the screening of an agent to determine its effect on the frequency of genome rearrangement in mammals. In particular, mice harboring a p.sup.un mutation are exposed to an agent of interest and the frequency of genome rearrangement relative to that observed in an unexposed mouse is determined. The relative frequency of rearrangement represents a measure of the effect of the agent on the host animal.
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