Synthesis of hydroxysulfone and related compounds

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United States of America Patent

PATENT NO 5760249
SERIAL NO

08704195

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Abstract

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This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma.

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Patent Owner(s)

Patent OwnerAddress
ZENECA LIMITEDIMPERIAL CHEMICAL HOUSE 9 MILLBANK LONDON SW1P 3JF

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blacker, Andrew J North Rigton, GB 6 18
Mathre, David J Skillman, NJ 23 116
Moody, David Fife, GB6 10 7
Sohar, Paul Warren, NJ 11 42

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