Human liver epithelial cell lines

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United States of America Patent

PATENT NO 5759765
SERIAL NO

08458878

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Abstract

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Immortalized cell lines derived from normal adult human liver are described which express phenotypic characteristics of normal adult liver epithelial cells. The invention further provides methods of using the immortalized cells to evaluate the cytotoxicity or carcinogenicity of a compound.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICESROCKVILLE MARYLAND 20852

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cole, Katharine H Dayton, MD 4 89
Harris, Curtis C Bethesda, MD 68 561
Lechner, John F Albuquerque, NM 10 214
Reddel, Roger St. Ives, AU 3 56

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