Bis-indolyl maleinimide or indolopyrrolo carbazole containing an amino acid as PKC inhibitors
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United States of America Patent
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May 12, 1998
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N/A
app pub date -
Nov 15, 1996
filing date -
Dec 21, 1992
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Abstract
The instant invention is a compound of formula A--X--Y--E.sub.n --R.sup.5 in which A is a bis-indolylmaleinimide or indolopyrrolocarbazole useful in the treatment and/or prevention of cancer, viral diseases, thrombosis, heart rhythm disturbances, atherosclerosis, bronchopulmonary diseases, degenerative diseases of the central nervous system, inflammatory diseases, diseases of the immune system, psoriasis, and immune suppression. A pharmaceutical composition and methods of preparing the compounds are also included.
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