1,3,8-triaza- and 3,8-diaza-1-oxaspiro ?4,5! decane derivatives
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United States of America Patent
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Apr 14, 1998
Grant Date -
N/A
app pub date -
Jun 20, 1996
filing date -
Jun 23, 1995
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Expired
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Abstract
Heterocyclic compounds of Formula I: ##STR1## in which n is 2, 3, 4, 5 or 6; t is 1, 2, 3 or 4; u is 0 or 1 (provided that t is not 1 when u is 0); X is O or N(R.sup.4); Y and Z are independently C(O), C(S) or CH.sub.2 (provided that Y and Z are not both CH.sub.2); R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are as defined in the specification; and their pharmaceutically acceptable salts and N-oxides, formulations containing them, their uses as therapeutic agents, and their synthesis.
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