(+) and (-)-8-chloro-6-sulfonyloxy-octanoic acid, its derivatives, and methods for making
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United States of America Patent
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Mar 24, 1998
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N/A
app pub date -
Aug 29, 1996
filing date -
Sep 13, 1995
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Expired
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Abstract
The synthesis of pure enantiomers of 8-chloro-6-sulfonyloxy-octanoic acids and their alkyl esters and of pure enantiomers of 6,8-dichloro-octanoic acid and its alkyl esters as intermediates for the synthesis of the enantiomers of .alpha.-liponic acid as well as a method for converting the two enantiomers of 8-chloro-6-hydroxy-octanoic acid into an enantiomer of .alpha.-liponic acid.
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