Inhibitors of adenosine monophosphate deaminase

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United States of America Patent

PATENT NO 5731432
SERIAL NO

08192154

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Abstract

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Novel diazepine derivatives which selectively inhibit adenosine monophosphate deaminase and methods of preparing these compounds are provided. These compounds are useful in treating certain conditions in vivo which may be ameliorated by increased local concentrations of adenosine.

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Patent Owner(s)

Patent OwnerAddress
METABASIS THERAPEUTICS INC9390 TOWN CENTRE DRIVE SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bookser, Brett C Solana Beach, CA 21 72
Erion, Mark D Del Mar, CA 67 1993
Gruber, Harry E Rancho Santa Fe, CA 66 879
Kasibhatla, Srinivas Rao San Diego, CA 37 666

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