Potentiation of temozolomide in human tumour cells

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United States of America Patent

PATENT NO 5731304
SERIAL NO

08448384

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Abstract

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The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O.sup.6 -benzylguanine.

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Patent Owner(s)

Patent OwnerAddress
CANCER RESEARCH CAMPAIGN TECHNOLOGYREGENT'S PARK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baer, John Colin London, GB2 1 18
Freeman, Azadeh Alison Croydon, GB2 1 18
Margison, Geoffrey Paul Poynton, GB2 3 43
Newlands, Edward Stuart London, GB2 1 18
Rafferty, Joseph Anthony Edgeley Stockport, GB2 4 57
Watson, Amanda Jean Godley Hyde, GB2 4 57

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