Process for making an epoxide

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United States of America Patent

PATENT NO 5728840
SERIAL NO

08512602

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Abstract

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A process for synthesizing the epoxide of the formula ##STR1## consists of, at a minimum, formation of a halohydrin from the allyl acetonide reactat, followed by base-induced cyclization, the epoxide product I being useful as an intermediate for the synthesis of inhibitors of renin or HIV protease or other proteases.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME CORP126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Askin, David Warren, NJ 38 216
Eng, Kan K Jersey City, NJ 7 33
Maligres, Peter E Scotch Plains, NJ 23 52
Reider, Paul J Westfield, NJ 24 97
Rossen, Kai Westfield, NJ 50 283
Upadhyay, Veena Edison, NJ 3 8
Volante, Ralph P Cranbury, NJ 66 368
Weissman, Steven A Little Falls, NJ 15 71

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