Method of preparing phosphodiesterase IV inhibitors
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United States of America Patent
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Mar 17, 1998
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N/A
app pub date -
Apr 2, 1997
filing date -
Apr 17, 1996
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Expired
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Abstract
A process for the preparation of a compound of structural formula I ##STR1## wherein R.sup.1 is alkyl, alkenyl, phenyl or substituted phenyl, which comprises the addition of R.sup.1 to an intermediate 2: ##STR2## by treatment of 2 with (R.sup.1).sub.3 M followed by reductive removal of the sulfinyl group.
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