Recombinant antigen for diagnosing rheumatoid arthritis
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United States of America Patent
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Mar 3, 1998
Grant Date -
N/A
app pub date -
Apr 10, 1996
filing date -
Feb 19, 1993
priority date (Note) -
Expired
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Abstract
A method is described for diagnosing rheumatoid arthritis by providing a recombinant antigen (RAMA) and detecting rheumatoid arthritis-associated IgM antibodies against the RAMA antigen in patient sera. The RAMA antigen comprises SEQ ID NO:3 and peptides substantially homologous thereto. A purified and isolated DNA encoding the RAMA antigen and a transformed host containing the DNA are also disclosed.
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