Animal cell culturing media containing N-acetyl-L-glutamic acid
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United States of America Patent
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Feb 17, 1998
Grant Date -
N/A
app pub date -
Dec 16, 1994
filing date -
Dec 24, 1993
priority date (Note) -
Expired
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Abstract
The present invention relates to a medium composition for culturing animal cells which is obtained by combining at least one component selected from the group of substances mentioned below with a medium composition comprising inorganic salts, saccharides, vitamins and amino acids; a method for culturing animal cells comprising adding to a medium for the cells as a cell growth promoting substance at least one component selected from the group mentioned below; a method for enhancing the antibody production of antibody-producing cells comprising adding to a medium for the cells at least one component selected from the group mentioned below; a composition for enhancing the antibody production of antibody-producing cells which is obtained by combining at least one antibody production enhancing agent selected from the group mentioned below with a composition comprising inorganic salts, saccharides, vitamins and amino acids; and a method for producing a physiologically active substance comprising culturing animal cells on a medium containing at least one cell growth promoting substance selected from the group mentioned below, and then harvesting the cells grown or the substances produced by the cells. D-penicillamine or salts thereof Acetoacetic acid or salts thereof Biguanides Vitamin K.sub.5 or salts thereof N-acetyl-L-glutamic acid or salts thereof.
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