Methods of treating circadian rhythm disorders
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United States of America Patent
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Feb 10, 1998
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N/A
app pub date -
May 30, 1995
filing date -
Dec 4, 1990
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Abstract
A method for treating circadian rhythm disorders is described. The method involves the administration of melatonin from about 6 hours to about 19 hours prior to when the normal sleep phase should begin, depending on whether a phase advance shift in circadian rhythms or a phase delay shift is desired. This is typically from about 4 hours to about 17 hours prior to the time of endogenous melatonin onset.
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