Diagnostic test for Pseudomonas aeruginosa infections
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United States of America Patent
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Feb 10, 1998
Grant Date -
N/A
app pub date -
May 30, 1995
filing date -
Jan 15, 1987
priority date (Note) -
Expired
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Abstract
Methods and reagents are provided for a novel immunodiagnostic test for the presence of P. aeruginosa in a biological sample. Monoclonal antibodies are employed which bind to an outer membrane protein antigen, which may be exposed by a solubilizing reagent. The antibody binds substantially all strains of P. aeruginosa. No cross-reactivity with other species of Pseudomonas or with other clinically significant gram-negative or gram-positive species is observed. Conjugating the monoclonal antibody of the invention with a fluorescent label provides for a rapid and sensitive direct immunofluorescent test for P. aeruginosa.
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