3-amino-2-oxo-1-piperidineacetic derivatives containing an arginine mimic as enzyme inhibitors

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United States of America Patent

PATENT NO 5714499
SERIAL NO

08261498

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Abstract

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The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

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Patent Owner(s)

Patent OwnerAddress
DENDREON PHARMACEUTICALS INC400 SOMERSET CORPORATE BOULEVARD BRIDGEWATER NJ 08807

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Levy, Odile E San Diego, CA 8 87
Nutt, Ruth F San Diego, CA 38 587
Ripka, William C San Diego, CA 12 164
Semple, Joseph E San Diego, CA 19 114

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