Benzoazine derivative or salt thereof and pharmaceutical compostion comprising the same

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United States of America Patent

PATENT NO 5710152
SERIAL NO

08791269

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A benzoazine derivative represented by the following formula (1), ##STR1## wherein R.sup.1 represents an alkyl group, alkoxy group, halogen atom, halogenoalkyl group, amino group, hydroxy group, benzyloxy group which may have a substituent, cyano group, carbamoyl group, acyl group, nitro group, carboxy group, or sulfonamide group; R.sup.2 and R.sup.3 may be the same or different and each individually represents a hydrogen atom or an alkyl group, or R.sup.2 and R.sup.3 indicate in combination an alkylene group having 2-7 carbon atoms; R.sup.4 and R.sup.5 may be the same or different and each individually represents a hydrogen atom or an alkyl group; X denotes O, S, or N--R.sup.6 (wherein R.sup.6 represents a hydrogen atom, an alkyl group, or an aryl group or pyridyl group which may have a substituent); m is an integer from 0 to 4; and n is an integer from 1 to 3, or a salt of the benzoazine derivative. The compound exhibits superior effects for reducing blood glucose value, plasma insulin value, and plasma triglyceride value, and is useful as a medicament for preventing or treating diabetes, hyperlipidemia, and obesity.

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Patent Owner(s)

Patent OwnerAddress
SS PHARMACEUTICAL CO LTDTOKYO JAPAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Honda, Haruyoshi Tomisato-machi, JP 13 96
Ito, Yoshikuni Narita, JP 36 569
Kotake, Jiro Ichikawa, JP 1 11
Kouda, Tadayuki Narita, JP 6 19
Matsuda, Hideaki Abiko, JP 116 1160
Nagao, Yoshihiro Narita, JP 7 40
Sato, Susumu Narita, JP 259 2888

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