Method for the preparation of in vitro-derived human neutrophil precursor cells
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United States of America Patent
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Dec 23, 1997
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app pub date -
Sep 13, 1996
filing date -
Mar 23, 1992
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Abstract
A composition of human neutrophil precursor cells is disclosed wherein at least 16% of the cells are human myeloblasts and promyelocytes. The myeloblasts and promyelocytes are derived from human neutrophil progenitor cells that were obtained from peripheral blood, bone marrow or cord blood. The neutrophil precursor cells contain less than 5% colony forming units. Also disclosed are human neutrophil precursor cells made up of about 16% CD15+CD11b- cells and less than 5% colony forming units and methods of preparing these compositions.
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