Use of persistent free-radicals in magnetic resonance imaging
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United States of America Patent
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Dec 23, 1997
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N/A
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Apr 3, 1995
filing date -
Aug 9, 1991
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Abstract
The present invention relates to the use of persistent free radicals, in particular persistent free radicals having a carbon-based .pi.-bonded electronic system available for delocalization of the unpaired electrons as image enhancing agents in magnetic resonance imaging (MRI), in particular electron spin resonance enhanced magnetic resonance imaging (ESREMRI). The invention also relates to contrast media containing such radicals and to the use of such radicals and their non-radical precursors in the manufacture of MRI and ESREMRI contrast media.
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