Method for the immunological determination of the carboxyterminal propeptide of type I procollagen
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United States of America Patent
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Dec 16, 1997
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N/A
app pub date -
Jun 5, 1995
filing date -
Jun 26, 1990
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Abstract
A carboxyterminal propeptide of type I procollagen free from type III procollagen carboxyterminal propeptide can be used to produce an antibody which is specific for carboxyterminal propeptide of type I procollagen and which has no affinity for the type III procollagen carboxyterminal propeptide. This antibody can be used to assay more accurately the propeptide which is a measure of the rate of production of type I procollagen and useful in diagnosing and monitoring e.g. bone diseases.
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