Process for the manufacture of pharmaceutical grade ranitidine base
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United States of America Patent
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-
Dec 9, 1997
Grant Date -
N/A
app pub date -
Jun 24, 1994
filing date -
May 13, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A process for the manufacture of pharmaceutical grade ranitidine base(N-?2-???5-(Dimethylamino)methyl!-2-furanyl!methyl!thio!ethyl-N'-methyl-2-nitro-1, 1-ethenediamine), is described. In-vitro and in-vivo pharmacological studies and acute toxicity studies indicate that it is as active and as safe as Form 2 ranitidine hydrochloride.
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