Process for the preparation of substituted thiopyran-1-oxides

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United States of America Patent

PATENT NO 5688954
SERIAL NO

08633749

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A process is described for the preparation of a compound of formula (IX) from 4-hydroxybutyl 3-pyridyl ketone. The compound of formula (IX) is an intermediate useful in the preparation of (1R,2R)-2-(3-pyridyl)-N-alkyl-tetrahydro-2H-thiopyran-2-carbothioamide 1-oxides which possess useful pharmaceutical properties, for example anti-hypertensive properties. ##STR1##

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Patent Owner(s)

Patent OwnerAddress
RHONE-POULENC RORER LIMITED50 KINGS HILL AVENUE KINGS HILL RPR HOUSE WEST MALLING KENT ME19 4TA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leon, Patrick Tassin La Demi Lune, FR 25 99
Petre, Dominique Lyons, FR 13 197
Pitchen, Philippe Dagenham, GB 7 20
Powers, Matthew Barto, PA 5 18

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