C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)-3-phenylisoserine and production process therefor

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United States of America Patent

PATENT NO 5684175
SERIAL NO

08483081

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Abstract

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The synthesis of paclitaxel obtained from the semi-synthesis of taxol using a protected baccatin III backbone which is esterified with a suitably protected side chain acid, thereby producing an intermediate which may be acylated and deprotected to produce paclitaxel.

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Patent Owner(s)

Patent OwnerAddress
MAYNE PHARMA (USA) INCMACK CALI CENTRE II 650 FROM ROAD 2ND FLOOR PARAMUS NJ 07652

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chander, Madhavi C Rosemont, PA 13 132
Sisti, Nicholas J Jeffersonville, PA 14 157
Swindell, Charles S Merion, PA 28 861

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