3-aminopyrroles, methods for their synthesis and for their pharmaceutical use

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United States of America Patent

PATENT NO 5684160
SERIAL NO

08446000

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Abstract

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The invention is directed to 3-aminopyrroles of formula I, which are largely new, to methods for the preparation and to their use as medicinal agents and preparations, as well as to anti-convulsive or analgesic preparations containing these 3-aminopyrroles. Disubstituted and monosubstituted amino groups are claimed as 3-amino substituents. The invention pursues the objective of developing largely new 3-aminopyrroles, which have CNS activity, particularly ones which anti-convulsive or analgesic properties, as well as methods for their preparation and their use as medicinal preparations. Pursuant to the invention, the synthesis is carried out by cyclizing open-chain precursors, such as aminoacrylic acid derivative, or by modifying pyrroles.

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Patent Owner(s)

  • ARZNEIMITTELWERK DRESDEN GMBH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faust, Gottfried Berlin, DE 6 12
Knoll, Alexander Berlin, DE 5 273
Liebscher, Jurgen Berlin, DE 2 1
Lohman, Dieter Radebeul, DE 2 7
Morgenstern, Eveline Berlin, DE 2 7
Rolfs, Andreas Berlin, DE 4 16
Scharfenberg, Peter Wuppertal, DE 2 7
Uschmajew, Aleksej Berlin, DE 2 7

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