Pharmaceutical formulation comprised of polymyxintrimethoprim and an anti-inflammatory drug for ophthalmic and otic topical use
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United States of America Patent
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Oct 21, 1997
Grant Date -
N/A
app pub date -
Oct 27, 1995
filing date -
Oct 7, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
It comprises: 0.005-1.0% of trimethoprim or a pharmaceutically acceptable salt thereof: 0.01-0.3% of polymyxin or a pharmaceutically acceptable salt thereof: 0.001-5% of a steroidal or non-steroidal anti-inflammatory drug and, optionally, one or more ingredients selected from among isotonizing agents, pH buffers, viscosity modifying agents, wetting agents, chelating agents, anti-oxidants, preservatives and vehicles. The formulation has a pH between 4 and 8.5. It is applicable in the treatment of ophthalmic and otic infections accompanied by inflammation.
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