Immunosuppressant peptides

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United States of America Patent

PATENT NO 5679640
SERIAL NO

08400781

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Peptide compositions are provided which bind MHC molecules of interest and inhibit T cell activation. The peptide compositions of the present invention comprise various isosteres of naturally occurring amino acid sequences. Such compositions may be used to treat diseases associated with particular DR alleles, including autoimmune diseases such as rheumatoid arthritis.

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Patent Owner(s)

Patent OwnerAddress
PHARMEXA INC5820 NANCY RIDGE DRIVE SUITE 100 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arrhenius, Thomas S San Diego, CA 9 228
Gaeta, Federico C A La Jolla, CA 42 736
Grey, Howard M La Jolla, CA 26 686
Powell, Michael F San Francisco, CA 4 67
Sette, Alessandro D La Jolla, CA 6 151

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