Monoclonal antibodies for the selective immunological determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids

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United States of America Patent

PATENT NO 5679583
SERIAL NO

08417197

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Abstract

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It is possible with the aid of a monoclonal antibody which is specifically directed against an epitope of amino-terminal procollagen peptide (type III) which is not present on the fragment Col 1, and of a second monoclonal or polyclonal antibody against an epitope of amino-terminal procollagen peptide (type III), to determine said peptide with great accuracy. It is also, possible, with the aid of a monoclonal antibody which is specifically directed against an epitope of amino-terminal procollagen peptide (type III) which is not present in Col 1, to determine with great accuracy said procollagen peptide in body fluids.

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Patent Owner(s)

Patent OwnerAddress
AVENTIS PHARMA DEUTSCHLAND GMBH (AVENTIS PHARMA)INDUSTRIEPARK HOCHST-GEBAUDE K 802 65926 FRANKFURT AM MAIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brocks, Dietrich Wiesbaden, DE 21 168
Gunzler-Pukall, Volkmar Marburg, DE 8 87
Hachmann, Henning Frankfurt am Main, DE 3 14
Punter, Jurgen Hofheim am Taunus, DE 1 6
Strecker, deceased Helmut late of Pfungstadt, DE 4 33
Timpl, Rupert Gauting, DE 12 171

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