Derivatives of neuraminic acid
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United States of America Patent
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Oct 14, 1997
Grant Date -
N/A
app pub date -
Apr 26, 1995
filing date -
Aug 3, 1992
priority date (Note) -
Expired
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Abstract
Provided are new derivatives of neuraminic acid of formula (I), where Ac represents an acyl residue of an aliphatic, araliphatic, aromatic, alicyclic, or heterocyclic carboxylic acid, including carboxylic amides, their 2-hydrocarbyl-glycosides, and their peracylated derivatives at the hydroxy groups of both these series of amides. These compositions are therapeutically useful in providing a protective effect against the neurotoxicity induced by excitatory amino acids, and can therefore be used in therapies of the central nervous system. ##STR1##
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