Genetic modification of endothelial cells
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United States of America Patent
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Oct 7, 1997
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N/A
app pub date -
May 25, 1994
filing date -
Dec 11, 1987
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Abstract
Endothelial cells transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced endothelial cells are disclosed. Such endothelial cells are useful in improving the performance of vascular grafts and in delivering the encoded polypeptide or protein, such as an enzyme, a hormone, a receptor or a drug, to an individual.
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