Pyranones
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United States of America Patent
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-
Sep 23, 1997
Issued Date -
N/A
app pub date -
Mar 28, 1996
filing date -
Sep 20, 1991
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centres which comprises selective reaction of at least one isomer with a reagent catalysed by a hydrolase enzyme whereby at least one isomer is preferentially converted into a distinct chemical species from the other isomers so that it is susceptible of separation by an appropriate chemical or physical separation process in which the tetrahydropyran-2-one is of Formula (1): ##STR1## wherein: Z is --H or a protecting group susceptible of reaction with the reagent under the influence of the enzyme; and Y is formyl or protected formyl.
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Patent Citation Ranking
- 6 Citation Count
- C07D Class
- 18.13 % this patent is cited more than
- 28 Age