Aminophenylphosphonic acid compounds
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United States of America Patent
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Sep 23, 1997
Grant Date -
N/A
app pub date -
Jul 19, 1996
filing date -
Jul 21, 1995
priority date (Note) -
Expired
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Abstract
A compound of formula (I): ##STR1## in which: R.sub.1, R.sub.2, which may be identical or different, represent hydrogen or halogen, or alkyl, alkoxy, nitro or trihalomethyl, X represents CO, SO.sub.2 or CH.sub.2, A.sub.1 represents any one of the groups as defined in the description, A.sub.2 represents --(CH.sub.2).sub.n or --CH.dbd.CH--, R.sub.3, R.sub.4, which may be identical or different, represent hydrogen or alkyl, its isomers as well as its addition salts with a pharmaceutically acceptable base and medicinal product containing the same are useful as angiogenesis inhibitors.
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