Antitumor composition for oral administration
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United States of America Patent
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Sep 9, 1997
Grant Date -
N/A
app pub date -
Dec 12, 1995
filing date -
Dec 12, 1995
priority date (Note) -
Expired
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Abstract
An antitumor composition for oral administration, comprising a 2'-deoxy-2'-methylidenecytidine compound of the formula ##STR1## wherein R is a hydrogen or a halogen, and R.sup.1 and R.sup.2 are the same or different and each is a hydrogen, a halogen or an alkyl having 1 to 4 carbon atoms, an acid addition salt thereof or a hydrate thereof, and a sucrose ester of fatty acid(s). The pharmaceutical composition of the present invention comprising a DMDC compound useful as an antitumor agent based on its remarkable degenerative action on solid tumor shows an improved oral absorption.
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