Hydrogel adhesive for attaching medical device to patient
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United States of America Patent
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Sep 9, 1997
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Apr 4, 1994
priority date (Note) -
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Abstract
A biocompatible hydrogel adhesive which is prepared from a precursor containing acrylic acid and an alcoholamine and is adhesive under both wet and dry conditions. The use of diisopropanolamine provides these unexpected and unique wet tack properties and permits adhesion to wet tissue. Additionally, the use of a polyol which contains hydroxyl groups, such as glycerine, and a diamine, such as 2-methylpentamethylenediamine, is found to provide a hydrogel having wet adhesive properties and longer shelf life. The hydrogel adhesive can be used as an attachment means in conjunction with a biomedical detection or monitoring means. The adhesive may be used to attach a sensor on the skin of an intrautero fetus and to monitor the well being of the fetus during labor and delivery. The hydrogel having wet adhesive properties permits the attachment of a sensor or sensors onto wet tissue. The biocompatible adhesive is used to attach a fetal probe securely to a fetus. The adhesive can be used as an attachment means for a drug delivery or prosthetic device or as an attachment means for fixing a contraceptive device to the wall of the uterus. The attachment means could also be used in the oral cavity to fix a sensor or for oral therapies.
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