Administration system for estradiol
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United States of America Patent
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Sep 9, 1997
Issued Date -
N/A
app pub date -
Dec 19, 1994
filing date -
May 8, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The adhesive plaster for the transdermal administration of estradiol or mixture estradiol/progestin is composed of an impermeable carrier film and of an adhesive composition. The latter represents a matrix or reservoir layer and is composed of a solvent-based polyacrylate or polyisobutylene adhesive which contains a saturated or unsaturated fatty acid with 6 to 18 C atoms as permeability enhancer, estradiol or mixture estradiol/progestin as active substance and optionally propylene glycol as solvent. The adhesive plaster is used for the systemic administration of hormones in hormone replacement therapy for a time of at least 3 days.
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