Chiral compounds and their resolution synthesis using enantioselective esterases

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United States of America Patent

PATENT NO 5661014
SERIAL NO

08452677

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Abstract

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Enantiomeric glutarimides such as aminoglutethimide and rogletimide are prepared by cyclisation of a corresponding ester-nitrile which is a good substrate for biotransformation with an enantiospecific esterase.

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Patent Owner(s)

Patent OwnerAddress
CHIROSCIENCE LIMITEDCAMBRIDGE CB4 4WE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Evans, Christopher Thomas Hendon, Nr Royston, GB 3 47
McCague, Raymond Milton, GB 19 86
Taylor, Stephen John Clifford Ely, GB 7 5

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