Detection of inherited and somatic mutations of APC gene in colorectal cancer of humans

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United States of America Patent

PATENT NO 5648212
SERIAL NO

08289548

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. APC is a tumor suppressor.

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Patent Owner(s)

Patent OwnerAddress
THE JOHN HOPKINS UNIVERSITYBALTIMORE MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albertsen, Hans Salt Lake City, UT 17 447
Anand, Rakesh Cheshire, GB2 15 488
Carlson, Mary Salt Lake City, UT 9 482
Groden, Joanna Salt Lake City, UT 12 485
Hedge, Philip John Cheshire, GB2 7 360
Joslyn, Geoff Salt Lake City, UT 9 482
Kinzler, Kenneth Baltimore, MD 28 964
Markham, Alexander Cheshire, GB2 1 77
Nakamura, Yusuke Tokyo, JP 416 3218
Thliveris, Andrew Salt Lake City, UT 8 440
Vogelstein, Bert Baltimore, MD 338 7135
White, Raymond L Salt Lake City, UT 16 527

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