Method of treating chronic progressive vascular diseases

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United States of America Patent

PATENT NO 5643892
SERIAL NO

08478347

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Abstract

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A method of treating a mammalian patient suffering from a chronic progressive vascular disease (CPVD) characterized by scarring and/or fibrosis to halt the progress of the disease and cause resolution of already-formed scarring or fibrotic lesions. The method consists of the administration to the patient of a pharmaceutical composition containing an effective amount of pentosan polysulfate (PPS) or a pharmaceutically acceptable salt thereof. The oral route of administration is preferred, with total daily dosage of PPS or PPS salt ranging from about 50 to 1200 mg per day.

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Patent Owner(s)

Patent OwnerAddress
HEALTH AND HUMAN SERVICES DEPARTMENT OF UNITED STATES OF AMERICA THEP O BOX 13 6011 EXECUTIVE BLVD NATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY TRANSFER ROCKVILLE MD 20852

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sherman, Fred P Hollywood, FL 5 136
Striker, Gary E Bethesda, MD 9 32
Striker, Liliane J Bethesda, MD 4 20

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