Assay for determining sensitivity to activated protein C
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United States of America Patent
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Jul 1, 1997
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N/A
app pub date -
May 1, 1995
filing date -
Dec 3, 1993
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Abstract
An improved assay for determining sensitivity to activated protein C in test samples has been developed to ensure rapid and accurate evaluations. This assay is based on measuring the conversion, by activated factor VIII within a test sample, of added factor X to an activated form. The activated protein C sensitivity of the test sample is determined by the relative inhibition of factor X conversion as compared to a control. A test sample that has decreased sensitivity to activated protein C will show relatively low inhibition, and vice versa.
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