Autologous fibrin glue and methods for its preparation and use
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United States of America Patent
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Jul 1, 1997
Grant Date -
N/A
app pub date -
Apr 6, 1995
filing date -
Apr 6, 1995
priority date (Note) -
Expired
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Abstract
A fibrin glue includes a fibrinogen component and a thrombin component, both prepared from single donor plasma. The plasma is precipitated to produce a precipitate containing fibrinogen and a supernatant containing the thrombin. The precipitate may be resuspended in a small volume of supernatant and used as the fibrinogen component. The supernatant is further treated by clotting to convert residual fibrinogen to fibrin and filtration to remove the fibrin. The resulting serum can be used as the thrombin component.
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