Method for producing composition for solid medicine

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United States of America Patent

PATENT NO 5637322
SERIAL NO

08433351

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Abstract

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In producing a composition for solid medicine, comprising, as an active ingredient, a potassium channel activator and a pharmaceutically acceptable water-insoluble cellulose polymer, a method for producing a composition for solid medicine, which is characterized by dissolving a potassium channel activator in a solvent to give a medical solution, adding said medical solution to a water-insoluble cellulose polymer inert to said solvent in an amount necessary and sufficient to achieve a predetermined elution rate, homogeneously mixing them and drying the mixture to remove the solvent, and a composition for solid medicine, which is obtainable by said production method. According to the method of the present invention, elution rate of the active ingredient of a preparation comprising a potassium channel activator, which is a sustained release preparation, can be controlled with ease and with good reproducibility.

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Patent Owner(s)

Patent OwnerAddress
JAPAN TOBACCO INC1-1 TORANOMON 4-CHOME MINATO-KU TOKYO 1056927 ?1056927
YOSHITOMI PHARMACEUTICAL INDUSTRIES LTDOSAKA-SHI OSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ogawa, Kenji Chikujo-gun, JP 162 1625
Sugimori, Ken-ichi Takatsuki, JP 1 0
Tamura, Kiyoshi Takatsuki, JP 6 15

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