Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
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United States of America Patent
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Jun 3, 1997
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app pub date -
Mar 16, 1993
filing date -
Mar 16, 1993
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Abstract
A fluorocarbon emulsion which exhibits reduced pulmonary gas-trapping properties in species-sensitive laboratory animals is disclosed. Additionally, the fluorocarbon component(s) exhibit short organ retention time(s). The emulsion includes an aqueous phase, an emulsifier, and a fluorocarbon (or fluorocarbon composition), having a vapor pressure of less than about 8 torr to reduce pulmonary gas-trapping, and having an organ retention half life of less than about 6 weeks and more preferably less than about 3 to 4 weeks.
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